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Creators/Authors contains: "Chang, W. C."

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  1. ; ; ; ; ; ; ; ; ; ; et al ( , Physical Review C)
    Free, publicly-accessible full text available September 1, 2024
  2. ; ; ; ; ; ; ; ( , Biochemistry)
    Booker, S (Ed.)
    Applying enzymatic reactions to produce useful molecules is a central focus of chemical biology. Iron and 2-oxoglutarate (Fe/2OG) enzymes are found in all kingdoms of life and catalyze a broad array of oxidative transformations. Herein, we demonstrate that the activity of an Fe/2OG enzyme can be redirected when changing the targeted carbon hybridization from sp3 to sp2. During leucine 5-hydroxylase catalysis, installation of an olefin group onto the substrate redirects the Fe(IV)−oxo species reactivity from hydroxylation to asymmetric epoxidation. The resulting epoxide subsequently undergoes intramolecular cyclization to form the substituted piperidine, 2S,5S-hydroxypipecolic acid. 
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  3. ; ; ; ; ; ; ; ; ; ; et al ( , Nature)
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  4. ; ; ; ; ; ; ; ; ; ; et al ( , Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment)
    Free, publicly-accessible full text available October 1, 2024
  5. ; ; ; ; ; ; ; ; ; ; et al ( , Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment)
    Free, publicly-accessible full text available August 1, 2024
  6. ; ; ; ; ; ; ; ; ; ; et al ( , Physics Letters B)
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  7. ; ; ; ; ; ; ; ; ; ; et al ( , Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment)
    Free, publicly-accessible full text available July 1, 2024
  8. ; ; ; ; ; ; ; ; ; ; et al ( , Nature)
    null (Ed.)
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  9. ; ; ; ; ; ; ; ; ; ; et al ( , Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment)
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  10. ; ; ; ; ; ; ; ; ; ; et al ( , Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment)
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